Abstract

Introduction. The global devastating pandemic coronavirus disease 2019 (COVID-19) is a worldwide multisystemic infection caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has emerged as a menace to the global public health and countries economy. There is a crucial necessity for the suggestion of effective drugs to eliminate the virus outbreak. Several candidate drugs with existing emerging evidence try to offer a pharmacological strategy that may inhibit infection in COVID-19 patients. By, October 2020, scientists have nominated some reliable and safe types of coronavirus vaccines like Pfizer, Moderna, AstraZeneca, CureVac, CoronaVac, etc. that are effective and showed 95% to 90% protection, respectively. Aim. This review highlights important clinical and in vitro studies, uses of potent antiviral drugs and most recent vaccines against COVID-19 disease.