Abstract

This review evaluates the findings of available clinical literature on the use of platelet-rich plasma (PRP) to develop evidence-based recommendations for treating various musculoskeletal issues that arise in veterinary practice. The use of PRP-based treatments for various orthopedic conditions is rapidly evolving as a promising treatment modality; however, its true effectiveness has yet to be elucidated. Application of PRP has been reported in humans for a variety of orthopedic conditions. Although the majority of the veterinary literature on PRP reports its use in equine patients, there is a dearth of evidence addressing its use in canine patients. Nevertheless, evidence of the efficacy of PRP has appeared to be highly variable depending on its specific indication, particularly in musculoskeletal disorders. This review aims to present the available information on the efficacy of PRP therapy in veterinary orthopedic conditions and describes factors influencing its use, the limitations of PRP therapy, and future directions of PRP research and therapy.