Abstract

The purpose of this study was to evaluate the haematological and biochemical changes in Nigerian dogs with short bowel syndrome. Thirty adult dogs each weighing approximately 12.4kg (range 7-18kg) were used in this study. The dogs were randomized into five groups of six dogs each. Group 1 is the control group. The dogs here were not placed on any treatment. Group 2 dogs were supplemented with glutamine. Group 3 dogs were supplemented with honey. Group 4 dogs were supplemented with ascorbic acid and group 5 dogs were supplemented with glutamine, honey and ascorbic acid combination. Haematological parameters, serum electrolytes (Sodium, potassium, bicarbonate and, chloride) and enzymes (alanine aminotransferase, aspartate aminotransferase and alkaline phosphatase) were also evaluated. There was no depletion in sodium, potassium, bicarbonate and chloride in all the animals as the value of these electrolytes had remained at normal range in all five groups. There was a significant decrease in the value of alkaline phosphatase in the five groups and non significant changes in the value of alanine aminotransferase in all the animals. It was therefore, concluded that patients with resection of proximal small intestinal tract have better chances of survival than patients with a resected distal small intestinal tract.