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Mixed mammary carcinosarcoma in domesticated Asian palm civet (Paradoxurus hermaphroditus)

(2019) Mixed mammary carcinosarcoma in domesticated Asian palm civet (Paradoxurus hermaphroditus). World's Veterinary Journal. pp. 46-51. ISSN 23224568 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

A female Asian palm civet (Paradoxurus hermaphroditus), three years old was carried for a medical checkup to Ruddy animal's clinic in Sidoarjo, East Java, Indonesia. The civet suffers enlargement of abdominal mammary glands, painless lump, asymmetric size (4.1 and 8.4 cm in diameter), and lacerated wound on the large one with severe haemorrhage. The unilateral mastectomy was conducted under anaesthesia to handles both haemorrhage and tumour mass. Following the surgery, the tumour mass was stored in 10% neutral buffer formalin for histopathology using Hematoxylin & Eosin (H&E) staining and immunohistochemistry against antibody, anti-CD4+ and CD8+, further, a blood sample collected before and after surgery (on days: 0, 7, 30, and 60) for representing the healing progress. The chemotherapy was given using the combination of oral cyclophosphamide and intravenous injection of vincristine. According to laboratory results, the final diagnosis was mixed mammary carcinosarcoma with minimal expression of CD8+, notwithstanding, it showed the better prognosis after surgery and chemotherapy.

Item Type: Article
Keywords: Asian palm civet, CD4+, CD8+, Mixed mammary carcinosarcoma, Therapy
Subjects: Q Science > Q Science (General)
S Agriculture > SF Animal culture
Divisions: World's Veterinary Journal (WVJ)
Page Range: pp. 46-51
Journal or Publication Title: World's Veterinary Journal
Journal Index: Scopus
Volume: 9
Number: 1
Publisher: Scienceline Publication, Ltd
Identification Number: https://doi.org/10.36380/scil.2019.wvj7
ISSN: 23224568 (ISSN)
Depositing User: Dr. Alireza Sadeghi
URI: http://eprints.science-line.com/id/eprint/499

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