Abstract

The present work aimed to evaluate the effects of Mangifera indica leaf powder (MLP) on reproductive hormones, biomarkers of oxidative stress and toxicity, growth and carcass characteristics of female Cavia porcellus. 40 female guinea pigs (Cavia porcellus L.) aged 2 months with an average weight of 257.65±11.28 g were used. These guinea pigs were weighed, then randomly divided into 4 groups of 10 animals each and subjected to the following rations: T0 (basic diet), T1, T2 and T3 (basic diet + 0.50; 0.75 and 1 MLP, respectively). For 45 days, the guinea pigs of all groups received ad libitum drinking water and the corresponding experimental rations. Reproductive hormones analyses showed a significant (P<0.05) rise in serum progesterone concentration in the highest dose of MLP-treated guinea pigs. Malondialdehyde level was lowest in guinea pigs given feed with the highest dose of MLP while superoxide dismutase and catalase activities were maximum in animals that received the highest doses of MLP. Total Peroxidase activity was greatest in animals fed with the higher MLP dose. The lowest level of cholesterol was noticed in the group that received the greatest dose of MLP. Feed consumption was higher in guinea pigs receiving 0.75 and 1 MLP. The body weight gain and average daily gain had higher values in the subjects fed with MLP feed than those of the control group. Feed efficiency values were improved in animals that that were given 0.5 and 1 MLP with regards to those fed without MLP, the length of small intestine was higher (P<0.05) in 0.75 MLP-treated animals than the other groups, while the greatest value for the density of big intestine was recorded in those that received 0.25 MLP. Based on these values (1 of diet as optimum level), MLP can be used in feed to improve animal production performance. © The Author(s) 2024