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THE POLYMORPHISM OF LEPTIN AND THYROGLOBULIN GENES IN LAI SIND AND LAI BRAHMAN CATTLE

(2024) THE POLYMORPHISM OF LEPTIN AND THYROGLOBULIN GENES IN LAI SIND AND LAI BRAHMAN CATTLE. Online Journal of Animal and Feed Research. pp. 165-170. ISSN 22287701

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Abstract

The aim of this study was to investigate the single nucleotide polymorphisms (SNPs) present in intron 2 region of leptin (LEP) and 5’ untranslated region of thyroglobulin (TG5) genes in Lai Sind and Lai Brahman cattle populations raised in the Central Vietnam. For each cattle group, fifty hair root samples were collected and extracted genomic DNA. The LEP/Sau3AI and TG5/PsuI gene polymorphisms were analyzed using PCR-RFLP technique. The results showed that the SNPs of LEP/Sau3AI and TG5/PsuI were found in the both cattle groups. Three LEP/Sau3AI genotypes were detected, including LEPAA, LEPAB and LEPBB. All of the investigated cattle carried TG5CT genotype. The Hardy-Weinberg equilibrium was reached in the both cattle populations for LEP/Sau3AI, but not for TG5/PsuI. The polymorphisms at these two loci were moderate in the both cattle populations. It can be concluded that the SNPs LEP/Sau3AI and TG5/PsuI can be used as genetic markers for molecular selection in these cattle groups. A selection program is needed to increase the frequency of TG5T allele in Lai Sind and Lai Brahman cattle groups to improve beef marbling score. © The Author(s) 2024

Item Type: Article
Keywords: Cattle; Lai Brahman; Lai Sind; Leptin gene; Polymorphism; Thyroglobulin gene
Subjects: S Agriculture > SF Animal culture
Divisions: Online Journal of Animal and Feed Research (OJAFR)
Page Range: pp. 165-170
Journal or Publication Title: Online Journal of Animal and Feed Research
Journal Index: Scopus
Volume: 14
Number: 3
Publisher: Scienceline Publication
Identification Number: https://doi.org/10.51227/ojafr.2024.20
ISSN: 22287701
Depositing User: Dr. Saeid Chekani-Azar
URI: http://eprints.science-line.com/id/eprint/1122

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