Borges, L. P. B. and de Mattos-Junior, E. and Silva, M. A. M. and dos Santos, M. A. A. P. and Garcia, D. O. and Ayer, I. M. and Barros, F. F. P. C. and Teixeira, P. P. M. (2018) Effect of vitamin E on the prevention of peritoneal adhesions in sheep. World's Veterinary Journal. pp. 90-94. ISSN 23224568 (ISSN)
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WVJ 8(4) 90-94, Dec 25, 2018.pdf - Published Version Download (2MB) |
Abstract
The objective of this study was to assess vitamin E solution on the prophylaxis of intraperitoneal adhesions in ovine uterine serosal damage model with bipolar diathermy. Therefore, 19 ewes underwent laparotomy for induction of adhesions, using a uterine serosal bipolar electrocauterization model. Cauterizations were performed on the right uterine horn serosa and right ovary. Ewes were randomly divided into three groups: control group (GCT, n=5), with no treatment following electrocoagulation, another group using local rinse of 20 mL of normal saline (GNS, n=8), and the last group using local rinse of 20 mL of vitamin E injection solution (GVE, n=6). On day 21 postoperative, animals underwent laparoscopy for scoring and comparison of intraperitoneal adhesion according to frequency and number. The number of adhesions was compared among groups using the Kruskal-Wallis test and Dunn’s post-hoc test. As results, the bipolar uterine serosal coagulation model triggered uterine adhesions in 74% (14/19) of the animals. Frequency of postoperative intraperitoneal adhesions was similar (P= 0.819) among groups (80% ewes of GCT, 62.5% of GNS and 83% of GVE). There was no significant difference between treatment groups, however, number of adhesions was lower in GVE and GNS groups than in control group (P= 0.032), showing that the addition of these kind of substances are better than not using any type of barrier to prevent the formation of intraperitoneal adhesions.
| Item Type: | Article |
|---|---|
| Keywords: | Adhesions, Bipolar diathermy, Laparoscopy, Sheep, Uterus |
| Subjects: | Q Science > Q Science (General) S Agriculture > SF Animal culture |
| Divisions: | World's Veterinary Journal (WVJ) |
| Page Range: | pp. 90-94 |
| Journal or Publication Title: | World's Veterinary Journal |
| Journal Index: | Scopus |
| Volume: | 8 |
| Number: | 4 |
| Publisher: | Scienceline Publication, Ltd |
| ISSN: | 23224568 (ISSN) |
| Depositing User: | Dr. Alireza Sadeghi |
| URI: | https://eprints.science-line.com/id/eprint/391 |
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