EFFECT OF SUPPLEMENTED Cordyceps militaris EXTRACT ON DISEASE RESISTANCE AND SURVIVAL RATE OF STRIPED CATFISH (Pangasius hypophthalmus) FINGERLINGS

Lan, Trinh Thi and Hang, Nguyen Thi Thuy and Hanh, Nguyen Thi Bich and Mai, Vo Phuong and Vy, Phan Nguyen Thai and Nhi, Nguyen Huu Yen (2026) EFFECT OF SUPPLEMENTED Cordyceps militaris EXTRACT ON DISEASE RESISTANCE AND SURVIVAL RATE OF STRIPED CATFISH (Pangasius hypophthalmus) FINGERLINGS. Online Journal of Animal and Feed Research. 01 - 09. ISSN 22287701

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Abstract

The effects of supplemented Cordyceps militaris extract in diets has been studied on the survival and immune response of striped catfish (Pangasius hypophthalmus) fingerlings with bacterial challenge conditions. The experiment was conducted for 60 days with six treatments and three replicates, including negative and positive controls with four dietary supplementation levels of C. militaris extract (0.18, 0.24, 0.36, and 0.47). After the feeding trial, striped catfish were challenged with Edwardsiella ictaluri at a dose of 10⁵ CFU/mL. Results showed that survival rates of striped catfish increased significantly with higher extract levels, reaching the highest value (70) at 0.47 supplementation compared with only 16.67 in the positive control group. Hematological indices such as red blood cell (RBC) and white blood cell (WBC) including lymphocytes, monocytes, and neutrophils increased proportionally with extract concentration, which can indicate enhanced immune responses. In conclusion, the findings suggest that dietary supplementation of C. militaris extract at 0.47 improves the disease resistance and health status of striped catfish fingerlings against E. ictaluri infection. This result highlights the potential application of C. militaris extract as a natural immunostimulants to enhance survival and reduce antibiotic use in catfish aquaculture. © The Author(s) 2026

Item Type:	Article
Keywords:	Cordyceps militaris; Edwardsiella ictaluri; Immune response; Pangasius hypophthalmus; Survival rate
Subjects:	S Agriculture > SF Animal culture
Divisions:	Online Journal of Animal and Feed Research (OJAFR)
Page Range:	01 - 09
Journal or Publication Title:	Online Journal of Animal and Feed Research
Journal Index:	Scopus
Volume:	16
Number:	1
Publisher:	Scienceline Publications, Ltd
Identification Number:	https://doi.org/10.51227/ojafr.2026.1
ISSN:	22287701
Depositing User:	Dr. Saeid Chekani-Azar
URI:	https://eprints.science-line.com/id/eprint/1794

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