EFFECT OF Nigella sativa OIL ON LIVER FUNCTION AND LIPID PROFILE IN BROWN, ALBINO AND LOCAL RABBITS: A COMPARATIVE STUDY

HASAN, Warvin Idrees and HIDAYET, Hoger Mardan and AZEEZ, Omar Hasan and SEFDEEN, Sherwan Mostafa and YATEEM, Cheya Ageed and MUSTAFA, Kamal Noaman (2026) EFFECT OF Nigella sativa OIL ON LIVER FUNCTION AND LIPID PROFILE IN BROWN, ALBINO AND LOCAL RABBITS: A COMPARATIVE STUDY. Online Journal of Animal and Feed Research. 109 - 117. ISSN 22287701

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Abstract

This study investigated the effects of Nigella sativa oil (NSO) on the metabolism of three rabbit breeds: Albino, Brown, and Local. A total of 48 rabbits were assigned to six groups and fed either a control diet or an NSO-supplemented diet (5 g/kg DM). Diets were alternated between groups every 15 days. Blood samples were analyzed for liver enzymes, kidney function parameters, lipid profile, thyroid hormones, and blood proteins. The results showed that NSO had no significant effect (P>0.05) on blood glucose, liver enzymes, or lipid profile. However, numerical differences were observed among breeds. Albino rabbits showed higher total cholesterol 83.6 and low-density lipoprotein (LDL) cholesterol (177.6) compared with the Local breed (P�0.01). Brown rabbits exhibited higher aspartate aminotransferase (AST) activity (60-64) than Albino rabbits (P�0.02). Additionally, brown rabbits showed higher (51.2) creatinine levels compared with Albinos (P�0.0001). Uric acid levels slightly increased (15-18) during the second treatment period. Protein levels remained relatively constant among groups; however, the brown breed had higher (P�0.02) albumin levels (9) than other breeds. In conclusion, rabbit breed had a greater influence on the measured parameters than dietary treatments which indicates that breed-specific genetic variations play an important role in such studies. © (2026), (Scienceline Publication). All rights reserved.

Item Type:	Article
Keywords:	Breeds; Lipid profile; Liver function; Neglia sativa; Rabbits.
Subjects:	S Agriculture > SF Animal culture
Divisions:	Online Journal of Animal and Feed Research (OJAFR)
Page Range:	109 - 117
Journal or Publication Title:	Online Journal of Animal and Feed Research
Journal Index:	Scopus
Volume:	16
Number:	2
Publisher:	Scienceline Publication
Identification Number:	https://doi.org/10.51227/ojafr.2026.13
ISSN:	22287701
Depositing User:	Dr. Saeid Chekani-Azar
URI:	https://eprints.science-line.com/id/eprint/1791

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