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Comprehensive overview, molecular epidemiology and antimicrobial resistance in Non-typhoid Salmonella

ALEMNEW, Marew and GELAW, Aschalew and NIBRET, Kindu and GETU, Addis and BERHANE, Nega (2023) Comprehensive overview, molecular epidemiology and antimicrobial resistance in Non-typhoid Salmonella. Journal of Life Science and Biomedicine. pp. 25-34. ISSN 2251-9939

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Official URL: http://dx.doi.org/10.54203/jlsb.2023.4

Abstract

Non-typhoid Salmonella (NTS) is a major public health problem affecting both humans and animals in many countries and being an important public health problem worldwide. It is a leading bacterial cause of diarrheal disease in humans, leading to gastroenteritis and deaths. It is a major agent of food-borne outbreaks as well as individual cases, especially in developing countries. Many virulence genes of Salmonella enterica are organized on SPIs (Salmonella pathogenicity islands). Twenty three SPIs are identified in genus Salmonella, which are required for adhesion, invasion, intra-cellular survival, and replication. Enhanced surveillance, improved food safety and responsible antibiotic use are crucial for preventing the spread of NTS. This review offers detailed information on NTS in an inclusive manner rather than fragmented approach. It also focuses on human NTS infections, unlike most research, which is conducted on animals.

Item Type: Article
Keywords: Antimicrobial resistance, Antimicrobial resistance gene, Salmonella, Non-typhoid Salmonella (NTS), Salmonella pathogenicity islands (SPIs)
Subjects: Q Science > QR Microbiology
R Medicine > RA Public aspects of medicine
R Medicine > RB Pathology
Divisions: Journal of Life Sciences and Biomedicine (JLSB)
Page Range: pp. 25-34
Journal or Publication Title: Journal of Life Science and Biomedicine
Journal Index: Not Index
Volume: 13
Number: 2
Publisher: Scienceline Publication
Identification Number: https://doi.org/10.54203/jlsb.2023.4
ISSN: 2251-9939
Depositing User: Dr. Zohreh Yousefi
URI: https://eprints.science-line.com/id/eprint/1281

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