TY  - JOUR
N1  - University of Lomé (UL), Regional Center of Excellence on Avian Sciences (CERSA), 01 BP: 1515, Lomé, Togo; University of Lomé (UL), Higher School of Agronomy (ESA), 01 BP: 1515, Lomé, Togo; Dan Dicko Dankoulodo University of Maradi (UDDM), Faculty of Agronomy and Environmental Sciences (FASE), BP: 465, Maradi, Niger; Bayero University Kano, Faculty of Agriculture, Department of Animal Science, PMB 3011, Kano, Nigeria
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85164569911&doi=10.54203%2fscil.2023.wvj26&partnerID=40&md5=0310600cec6fde0a5ecb18839de3886b
SP  - 240
Y1  - 2023/06/25/
AV  - public
A1  - Moustapha, A.
A1  - Talaki, E.
A1  - Akourki, A.
A1  - Ousseini, M.
KW  - fusion protein; HN protein; live vaccine; matrix protein; nucleoprotein; phosphoprotein; viral protein
KW  -  airborne transmission; Article; biosecurity; dehydration; demyelinating disease; drug efficacy; emaciation; encephalitis; false negative result; fecal oral transmission; gastrointestinal hemorrhage; genetic variability; genotype; geographic distribution; host; necrosis; nerve fiber degeneration; Newcastle disease; nonhuman; phagocytosis; poultry; proventriculus; real time reverse transcription polymerase chain reaction; reverse genetics; serotype; taxonomy; ulcer; vaccination; virus replication; virus resistance; virus shedding; virus strain; virus virulence
EP  - 249
VL  - 13
SN  - 2322-4568
TI  - Newcastle Disease Virus in Poultry: Current Status and Control Prospects
N2  - Since its first appearance in Java Island, Indonesia, in 1926, Newcastle disease has significantly impacted the global poultry industry, leading to substantial economic losses. The disease has rapidly spread worldwide, becoming endemic in many countries where agriculture is the primary source of national income. The present study aimed to present a comprehensive review of the recent literature on the Newcastle disease virus to contribute to understanding the virus and its control measures in poultry and provide an updated perspective on current knowledge. All strains of the Newcastle disease virus are classified under a single serotype; however, they are grouped into two classes and have been found to have emerging genetic diversity. Although various molecular diagnostic protocols have been developed, many have limitations. Nucleotide variability in the F gene of the Newcastle disease virus seems to explain the false-negative results provided by different real-time reverse transcription polymerase chain reaction protocols. Vaccination combined with biosecurity measures has been shown to limit the devastating effect of the Newcastle disease virus. However, the current vaccines are not effective enough to prevent viral shedding and infection of vaccinated animals. The efficacy of the vaccine strains utilized for decades is being scrutinized, raising questions about their effectiveness over time. The development of reverse genetics offers promising prospects for exploring new generations of attenuated vaccines capable of protecting poultry against clinical diseases and infections, such as Newcastle disease. © 2023, World''s Veterinary Journal. All Rights Reserved.
PB  - Scienceline Publication, Ltd
JF  - World's Veterinary Journal
IS  - 2
ID  - eprints800
ER  -