%X Dairy industry has recently grown as a very important economic national source of income. In Sudan, many dairy owners introduced foreign blood. This might result in a progeny of mixed blood cows with lowered resistance to endogenous and locally prevailing diseases such as mastitis. In this study 60 milk samples were obtained from Frisian cows in Elrudoan and Elmouileh Convention in Omdurman, Khartoum State, Sudan. Samples positive for bacterial growth were identified using the gram stain and various conventional biochemical tests. Hundred species of bacteria were isolated from 60 samples of milk. A total of 70 (70) were gram positive, and 30 (30) were gram negative bacteria. Among the total of the gram positive isolates, 40 (57.1) were Staphylococcus spp., 18 (25.7) were Bacillus spp., 6 (8.6) Streptococcus spp., 4 (5.7) Corynebacterium spp., and 2 (2.9) were Actinomyces spp. and from gram negative isolates, 26 (86.7) were Enterobacter spp. and 4 (13.3) were E. coli. Antibiotic susceptibility tests to Tylosin and Enroflaxcin were performed for the isolated bacteria (Staphylococcus aureus, Staph. epidermidis, Enterobacter aerogenes and Enterobacter faecalis). The isolated bacteria were found to be highly sensitive to Tylosin and Enrofloxacin. © 2020. All rights reserved. %P 53-57 %D 2020 %T IN VITRO EFFICACY OF TYLOSIN AND ENROFLOXACIN IN TREATMENT OF BOVINE MASTITIS CAUSING BACTERIA IN OMDURMAN LOCALITY %L eprints70 %I Scienceline Publication %R 10.36380/scil.2020.ojafr7 %V 10 %N 2 %J Online Journal of Animal and Feed Research %K Bovine Enroflxacin In vitro Mastitis Tylosin %A M. E. Almobarak %A R. R. M. Salih %A H. H. Gibreel