TY  - JOUR
TI  - NEW METHODS FOR DETOXIFICATION OF HEAVY METALS AND MYCOTOXINS IN DAIRY COWS
SP  - 81
SN  - 22287701 (ISSN)
EP  - 88
KW  - Cattle
KW  -  Heavy metals
KW  -  Mycotoxins
KW  -  Silage
KW  -  Sorption complex.
AV  - public
A1  - Baryshev, V. A.
A1  - Popova, O. S.
A1  - Ponamarev, V. S.
IS  - 2
PB  - Scienceline Publication
JF  - Online Journal of Animal and Feed Research
VL  - 12
Y1  - 2022/03/25/
ID  - eprints625
N2  - Among the many environmental and industrial factors that adversely affect the soil, the pollution with heavy metals and mycotoxins occupies a special place in livestock breeding. This study aimed to demonstrate methods of treating and pharmacological correction of a toxic state intensified by heavy metals and mycotoxins in cattle using native drug as mycotoxin-deactivating feed additive. A total of 20 highly productive Holstein cows aged 3-4 years were divided into 2 groups, based on clinical and biochemical parameters. The experimental group (n=10) fed a diet supplemented with 4% sorption complex and a drug based on Silybum marianum and ursodeoxycholic acid as a hepatoprotector named ?Hepaton-vet?. The control group (n=10) was injected with a complex of sorbents (consisting of perlite, vermiculite, and polyphepan in equal proportions) at a dose of 4% of the daily intake of food, and the rest of the treatment was carried out with the help of daily infusion therapy. So in the feed samples, only the T-2 and Deoxynivalenol (DON) indicators exceeded the normal value by 1.66% and, 3%, respectively. Thus, the practical efficiency concerning T-2, aflatoxin and Deoxynivalenol were to 100%, 86%, 18%, respectively. Cadmium in compound feed was lower by 44%, in comparison with the maximum permissible concentration, followed by 53.3% in hay and 78% in silage. The amount of lead in compound feed and silage was 78%, and it was 35% in the hay. In conclusion, the use of a complex of sorbents, together with newly developed component ?Hepaton-vet?, led to positive results, allowing for the identification of several effects that influenced the metabolic processes in the liver, which was confirmed by the results of morpho-biochemical blood tests and clinical diagnostics of the animals' condition.
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127470431&doi=10.51227%2fojafr.2022.11&partnerID=40&md5=0f4b98f2a7ef9281ffbe62b41ab9d465
ER  -