@article{eprints625,
           month = {March},
          author = {V. A. Baryshev and O. S. Popova and V. S. Ponamarev},
            year = {2022},
           pages = {81--88},
       publisher = {Scienceline Publication},
          number = {2},
          volume = {12},
           title = {NEW METHODS FOR DETOXIFICATION OF HEAVY METALS AND MYCOTOXINS IN DAIRY COWS},
         journal = {Online Journal of Animal and Feed Research},
        keywords = {Cattle, Heavy metals, Mycotoxins, Silage, Sorption complex.},
        abstract = {Among the many environmental and industrial factors that adversely affect the soil, the pollution with heavy metals and mycotoxins occupies a special place in livestock breeding. This study aimed to demonstrate methods of treating and pharmacological correction of a toxic state intensified by heavy metals and mycotoxins in cattle using native drug as mycotoxin-deactivating feed additive. A total of 20 highly productive Holstein cows aged 3-4 years were divided into 2 groups, based on clinical and biochemical parameters. The experimental group (n=10) fed a diet supplemented with 4\% sorption complex and a drug based on Silybum marianum and ursodeoxycholic acid as a hepatoprotector named ?Hepaton-vet?. The control group (n=10) was injected with a complex of sorbents (consisting of perlite, vermiculite, and polyphepan in equal proportions) at a dose of 4\% of the daily intake of food, and the rest of the treatment was carried out with the help of daily infusion therapy. So in the feed samples, only the T-2 and Deoxynivalenol (DON) indicators exceeded the normal value by 1.66\% and, 3\%, respectively. Thus, the practical efficiency concerning T-2, aflatoxin and Deoxynivalenol were to 100\%, 86\%, 18\%, respectively. Cadmium in compound feed was lower by 44\%, in comparison with the maximum permissible concentration, followed by 53.3\% in hay and 78\% in silage. The amount of lead in compound feed and silage was 78\%, and it was 35\% in the hay. In conclusion, the use of a complex of sorbents, together with newly developed component ?Hepaton-vet?, led to positive results, allowing for the identification of several effects that influenced the metabolic processes in the liver, which was confirmed by the results of morpho-biochemical blood tests and clinical diagnostics of the animals' condition.},
             url = {http://eprints.science-line.com/id/eprint/625/}
}