TY - JOUR UR - https://jlsb.science-line.com/attachments/article/81/JLSB%2010(6)%2070-79,%202020-drugs%20and%20vaccine%20candidates%20to%20tackle%20COVID-19%20.pdf SP - 70 Y1 - 2020/11/25/ AV - public A1 - GHARIB MOMBENI, Ehsan A1 - YOUSEFI, Mahshad A1 - CHEKANI-AZAR, Saeid A1 - ABOUSENNA, Mohamed Samy A1 - ARMIN, Kosar A1 - SHAVANDI, Fatemeh A1 - EMAMI, Elham A1 - BAHRAMI, Yadollah KW - Actemra KW - Antiviral medicines KW - ARCoV KW - AstraZeneca KW - ChulaCov19 KW - CoronaVac KW - COVID-19 KW - CureVac KW - CytoSorb KW - Ivermectin KW - Moderna KW - Oleandrin KW - Pfizer KW - Remdesivir KW - Ritonavir KW - Vaccines. EP - 79 VL - 10 SN - 2251-9939 TI - Recent drugs and vaccine candidates to tackle COVID-19 N2 - Introduction. The global devastating pandemic coronavirus disease 2019 (COVID-19) is a worldwide multisystemic infection caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has emerged as a menace to the global public health and countries economy. There is a crucial necessity for the suggestion of effective drugs to eliminate the virus outbreak. Several candidate drugs with existing emerging evidence try to offer a pharmacological strategy that may inhibit infection in COVID-19 patients. By, October 2020, scientists have nominated some reliable and safe types of coronavirus vaccines like Pfizer, Moderna, AstraZeneca, CureVac, CoronaVac, etc. that are effective and showed 95% to 90% protection, respectively. Aim. This review highlights important clinical and in vitro studies, uses of potent antiviral drugs and most recent vaccines against COVID-19 disease. PB - Scienceline Publications, Ltd JF - Journal of Life Science and Biomedicine IS - 06 ID - eprints559 ER -