%X The Patin catfish (Pangasius sp.) is a species of fish that is widely cultivated both in quarantine and in ponds. The success of Patin catfish cultivation is influenced by several factors, one of them is the feed. Patin catfish need essential amino acids to meet their needs. The addition of the amino acid (lysine) in the commercial feed not only affects the metabolism of the fish but also the content of Omega-3 and Omega-6 would be found in the fish. This study was conducted to observe the influences of essential lysine on the content of Omega-3 and Omega-6 of Patin catfish. This was an experimental study with a completely randomized design method, consisting of four treatments and five replications. The treatment which was given to experimental fish was commercial feed with the addition of lysine at different doses. The result indicated that the addition of lysine in commercial feed for 30 days of this research had a significant effect (p < 0.05) on the increase in the content of Omega-3 and Omega-6 in Patin catfish meat (Pangasius sp.). Based on the results of the current study, Patin catfish can be a good source of Omega-3 and omega 6 if the feed that is used in the cultivation process, contains lysine as an amino acid source. %K Cultivation, Lysine, Omega-3, Omega-6, Pangasius sp. %V 11 %P 263-266 %N 2 %R https://dx.doi.org/10.54203/scil.2021.wvj34 %A M. A. Yaqin %A A. Agustono %A W. Lokapimasari %D 2021 %J World's Veterinary Journal %I Scienceline Publication, Ltd %T The Effect of Essential Amino Acid (Lysine) in Commercial Feed of Patin Catfish (Pangasius sp.) %L eprints543