eprintid: 444
rev_number: 9
eprint_status: archive
userid: 5
dir: disk0/00/00/04/44
datestamp: 2022-05-09 00:14:14
lastmod: 2022-05-09 00:34:17
status_changed: 2022-05-09 00:14:14
type: article
metadata_visibility: show
creators_name: Hadi, M.
creators_name: Moghtadaei-Khorasgani, E.
creators_name: Etesamnia, M. H.
creators_id: moghtadaiee@gmail.com
title: The Influence of Basil Seed Hydroethanolic Extract on the Skin Wound Healing in Diabetic Male Rats
ispublished: pub
subjects: Q1
subjects: SF
divisions: j13
full_text_status: public
keywords: Basil, Diabetes, Histopathology, Wound
abstract: Diabetic wounds and cutaneous wounds are important issues in medical science. Basil is an herbaceous plant and has compounds such as terpenes, flavonoids, and antioxidant properties. A total of 50 male Wistar rats were allocated into 10 groups including the healthy group without treatment, the healthy group treated with 1% phenytoin, eucerin,  5% basil seed extract,  10% basil seed, diabetic group without treatment,  1% phenytoin,  eucerin. After anesthesia of rats, we made a 4 cm2 wound on the back of the animal, and different histopathological characteristics were examined, and also on days 3, 7, and 21, the area of wounds was analyzed. In the healthy group treated with 10% basil seed extract, it was revealed that the wound size was significantly healed in the research days. In the diabetic rat groups, the decrease in the wound area was not significant and there was no significant difference between groups. Histopathological findings on day 21  in the healthy group treated with 10% basil seed extract revealed proper epidermis formation and relatively dense dermis containing collagen filaments. While in the diabetic groups, healing was slower. The results indicated that basil extract with anti-inflammatory and antioxidant characteristics can quicken the repair of cutaneous wounds.
date: 2021-09-25
publication: World's Veterinary Journal
volume: 11
number: 3
publisher: Scienceline Publication, Ltd
pagerange: 377-383
id_number: https://dx.doi.org/10.54203/scil.2021.wvj49
refereed: TRUE
issn: 23224568 (ISSN)
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115422491&partnerID=40&md5=4b19a52103965ee58101fdc68d7a129e
j_index: scopus
citation:    (2021)     The Influence of Basil Seed Hydroethanolic Extract on the Skin Wound Healing in Diabetic Male Rats.   World's Veterinary Journal.  pp. 377-383.  ISSN 23224568 (ISSN)   
document_url: http://eprints.science-line.com/id/eprint/444/1/WVJ%2011%283%29%2C%20377-383%2C%20September%2025%2C%202021.pdf