TY - JOUR UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068065407&partnerID=40&md5=e9b26eac4e19c9189216dd81cbf8a463 SP - 90 Y1 - 2018/12/25/ AV - public A1 - Borges, L. P. B. A1 - de Mattos-Junior, E. A1 - Silva, M. A. M. A1 - dos Santos, M. A. A. P. A1 - Garcia, D. O. A1 - Ayer, I. M. A1 - Barros, F. F. P. C. A1 - Teixeira, P. P. M. KW - Adhesions KW - Bipolar diathermy KW - Laparoscopy KW - Sheep KW - Uterus EP - 94 VL - 8 SN - 23224568 (ISSN) TI - Effect of vitamin E on the prevention of peritoneal adhesions in sheep N2 - The objective of this study was to assess vitamin E solution on the prophylaxis of intraperitoneal adhesions in ovine uterine serosal damage model with bipolar diathermy. Therefore, 19 ewes underwent laparotomy for induction of adhesions, using a uterine serosal bipolar electrocauterization model. Cauterizations were performed on the right uterine horn serosa and right ovary. Ewes were randomly divided into three groups: control group (GCT, n=5), with no treatment following electrocoagulation, another group using local rinse of 20 mL of normal saline (GNS, n=8), and the last group using local rinse of 20 mL of vitamin E injection solution (GVE, n=6). On day 21 postoperative, animals underwent laparoscopy for scoring and comparison of intraperitoneal adhesion according to frequency and number. The number of adhesions was compared among groups using the Kruskal-Wallis test and Dunn?s post-hoc test. As results, the bipolar uterine serosal coagulation model triggered uterine adhesions in 74% (14/19) of the animals. Frequency of postoperative intraperitoneal adhesions was similar (P= 0.819) among groups (80% ewes of GCT, 62.5% of GNS and 83% of GVE). There was no significant difference between treatment groups, however, number of adhesions was lower in GVE and GNS groups than in control group (P= 0.032), showing that the addition of these kind of substances are better than not using any type of barrier to prevent the formation of intraperitoneal adhesions. PB - Scienceline Publication, Ltd JF - World's Veterinary Journal IS - 4 ID - eprints391 ER -