TY  - JOUR
ID  - eprints384
A1  - Batikh, M. M.
A1  - El-nabarawy, A. M.
A1  - Shakal, M. A. S.
A1  - Hegazy, A. H. M.
A1  - Morsy, E. A.
SP  - 745
Y1  - 2021/12/25/
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123238962&doi=10.54203%2fscil.2021.wvj95&partnerID=40&md5=4d00bc1df1e8c36a4cdeefea9e1ad6cb
TI  - The Effect of Mycotoxins in Naturally Contaminated Diet on the Pathogenicity of Escherichia coli in Broiler Chickens
KW  - Broiler chicken
KW  -  Clinicopathological finding
KW  -  Escherichia coli
KW  -  Histopathology
KW  -  Mycotoxin
KW  -  Organ colonization
PB  - Scienceline Publication, Ltd
IS  - 4
N2  - Contamination of feedstuffs with mycotoxins is considered a huge issue plaguing the poultry sector of Egypt. Therefore, the current study was conducted to examine the effect of the neglected natural mycotoxin contamination of ration on the clinicopathological picture of Escherichia coli infection in broiler chickens. A total of 240 one-day-old chicks were divided into 5 groups. The first 3 groups (1, 2, and 3) were further equally subdivided into 2 subgroups (A and B). Those in group A were fed on commercial ration treated with antimycotoxin while group B was fed on ration contaminated with mycotoxins. Groups 1, 2, and 3 were inoculated at one-day-old with E. coli O78, O128, and O157, respectively while group 4 was kept as a negative control and fed on a ration treated with antimycotoxin. Finally, group 5 was kept as positive controls and fed on a mycotoxin contaminated ration and inoculated with physiological saline. All groups contained 30 chicks. Results showed that the challenged groups fed on a ration containing mycotoxin had high mortality (23.3%) and also a high feed conversion ratio. Moreover, severe clinical symptoms, postmortem lesions, histopathological pictures, and a high rate of bacterial re-isolation were recorded. The pathological lesions were congestion of the liver, spleen, and kidneys in addition to severe pericarditis, perihepatitis, air sacullitis, ascites, and unabsorbed yolk sac. The histopathological changes included degeneration, necrosis, and liver inflammation with lymphoid depletion in the spleen and enteritis associated with sloughing of the mucosal epithelium. The obtained results were less severe in the challenged groups fed on a ration treated with antimycotoxin indicating combined action of both Escherichia coli and mycotoxins. In conclusion, the obtained results revealed that the mycotoxins even at low concentrations can augment the pathogenisity of Echerichia coli in broiler chickens.
JF  - World's Veterinary Journal
EP  - 757
VL  - 11
AV  - public
SN  - 23224568 (ISSN)
ER  -