%X Dermanyssus gallinae is one of the most common arthropods in layers that affects the quality and quantity of egg production. Although there are different synthetic compounds against this mite, but despite these compounds, drug resistance and the presence of these compounds and synthetic compounds in meat and eggs makes that the use of alternative methods, as well as increased use of herbal extracts and essential oils. In the present study, the N-Hexane and Ethanol extracts of Ferula assafoetida were used. GC-MS analysis revealed the constituents of the two extracts. The lethal properties of the extracts were determined by contact toxicity. In this field study, ethanolic extract of Ferula assafoetida was sprayed on laying hens that infected with red mite. The most available compounds of the Ethanol extract and N-hexan extract of Ferula assafoetida were Diethylpyridine and Aurapten respectively in this study. The LC50 of Ethanol extract of Ferula assafoetida was 16 µg/cm3 and in vitro study determined that ethanolic extract of Ferula assafoetida has been able to reduce the red mite population. This study indicated Ethanol extract of Ferula assafoetida could use as a substitute compound against red mite. %K Polar and nonpolar extract, Ferula assafoetida, Red mite %V 10 %P 429-435 %N 3 %R 10.36380/jwpr.2020.49 %A S. Ghavami %A K. Asasi %A M. Razavi %D 2020 %J Journal of World's Poultry Research %I Scienceline Publication, Ltd %T Effect of Polar and Non Polar Extract of Ferula Assafoetida Dermanyssus Gallinae in Vivo and in Vitro Conditions %L eprints198