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primary topic: Newcastle Disease Virus Infection in Domestic Pigeons: Epidemiology, Pathogenesis, Diagnosis, and Vaccination Strategies with Emphasis on Chitosan Nanoparticles

Newcastle Disease Virus Infection in Domestic Pigeons: Epidemiology, Pathogenesis, Diagnosis, and Vaccination Strategies with Emphasis on Chitosan Nanoparticles
type: AcademicArticle
type: Article
abstract: Newcastle disease virus (NDV), also known as avian paramyxovirus-1 (APMV-1), is a highly contagious pathogen that affects most avian species, including domestic pigeons (Columba livia), leading to Newcastle disease (ND). The ND in pigeons is attributed to pigeon-specific strains of NDV, predominantly characterized by the emergence of pigeon paramyxovirus-1 (PPMV-1). This viral strain is specifically adapted to affect avian species, particularly within the pigeon population, resulting in distinct pathological features associated with the disease. The ND was correlated with severe respiratory, neurological, and gastrointestinal manifestations, resulting in elevated morbidity and mortality rates, which may reach up to 80%. The present study provided an updated overview of the pathogenesis, clinical and pathological features, and diagnostic approaches related to NDV infection in domestic pigeons worldwide. Conventional and modern vaccination strategies were discussed in the present study, with a focus on mucosal immunization. Chitosan-based nanoparticles (CS-NPs) have emerged as a promising vaccine delivery platform due to their compatibility with biological systems, strong adhesion to mucosal surfaces, and ability to enhance antigen stability and stimulate the immune response. The CS-NPs improved antigen uptake at mucosal surfaces in poultry and stimulated both humoral and cellular immune responses, which included activating cytotoxic T cells, producing cytokines, and secreting immunoglobulins at mucosal sites. The present review may contribute to the advancement of more effective and targeted vaccine strategies against NDV in pigeons and other avian species.
date: 2025-09-25
volume: 15
issue: 3
is part of: Journal of World’s Poultry Research
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
has document: Newcastle Disease Virus Infection in Domestic Pigeons: Epidemiology, Pathogenesis, Diagnosis, and Vaccination Strategies with Emphasis on Chitosan Nanoparticles (Text)
has version: Newcastle Disease Virus Infection in Domestic Pigeons: Epidemiology, Pathogenesis, Diagnosis, and Vaccination Strategies with Emphasis on Chitosan Nanoparticles (Text)
has published: Newcastle Disease Virus Infection in Domestic Pigeons: Epidemiology, Pathogenesis, Diagnosis, and Vaccination Strategies with Emphasis on Chitosan Nanoparticles (Text)
subject: SF Animal culture

Newcastle Disease Virus Infection in Domestic Pigeons: Epidemiology, Pathogenesis, Diagnosis, and Vaccination Strategies with Emphasis on Chitosan Nanoparticles (Text)
type: Document
has file: JWPR15(3)407-417,2025 (1).pdf
has part: JWPR15(3)407-417,2025 (1).pdf

Scienceline Publication
type: Organization

Journal of World’s Poultry Research
type: Collection
issn: 2322455X

Harith Abdulla Najem
type: Person
given name: Harith
family name: Abdulla Najem

Muhammadtaher Abdulrazaq Abdulrasol
type: Person
given name: Muhammadtaher
family name: Abdulrazaq Abdulrasol

Wafaa A. Abd El-Ghany
type: Person
given name: Wafaa A.
family name: Abd El-Ghany

http://eprints.science-line.com/id/eprint/1631/
title: HTML Summary of #1631 <epc:when xmlns:epc="http://eprints.org/ep3/control" test="title">Newcastle Disease Virus Infection in Domestic Pigeons: Epidemiology, Pathogenesis, Diagnosis, and Vaccination Strategies with Emphasis on Chitosan Nanoparticles</epc:when>
format: text/html
primary topic: Newcastle Disease Virus Infection in Domestic Pigeons: Epidemiology, Pathogenesis, Diagnosis, and Vaccination Strategies with Emphasis on Chitosan Nanoparticles

SF Animal culture
type: Concept