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primary topic: Antibacterial Activities of Rosmarinus officinalis Extract against Enterococcus faecalis and Enterococcus faecium

Antibacterial Activities of Rosmarinus officinalis Extract against Enterococcus faecalis and Enterococcus faecium
type: AcademicArticle
type: Article
abstract: Hospital-acquired infections are caused by multidrug-resistant Enterococcus (E.) species, especially E. faecalis and E. faecium, which are zoonotic bacteria and pose a significant public health challenge. This study aimed to identify multidrug-resistant Enterococcus isolates and evaluate the antibacterial activity of Rosmarinus officinalis (R. officinalis) extract against E. faecalis and E. faecium. Fifty urine and stool samples were collected from hospitalized patients. Four multidrug-resistant strains—E. faecalis 6E, 7B, 10D, and E. faecium 15E—were identified by polymerase chain reaction (PCR) with universal primers (8F and 1492R) targeting the 16S rDNA gene to confirm their identity as Enterococcus species. The antibacterial efficacy of R. officinalis extract was assessed using disk diffusion and minimum inhibitory concentration (MIC) determination. High-Performance Liquid Chromatography (HPLC) analysis was conducted to identify phenolic bioactive compounds in R. officinalis. The extract demonstrated significant antibacterial activity, with MICs of 25 mg/mL and 30 mg/mL for E. faecalis and E. faecium, respectively. HPLC revealed phenolic compounds such as rosmarinic acid, caffeic acid, and ferulic acid, likely contributing to the antimicrobial properties. The R. officinalis extract could be a promising natural antimicrobial agent against multidrug-resistant Enterococcus species. Compounds such as rosmarinic acid, caffeic acid, ferulic acid, apigenin-7-glucoside, syringic acid, and p-hydroxybenzoic acid show potential as safer, environmentally friendly alternatives to traditional antibiotics, aiding in the fight against rising antibiotic resistance.
date: 2025-06-25
volume: 15
issue: 2
is part of: World’s Veterinary Journal
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
has document: Antibacterial Activities of Rosmarinus officinalis Extract against Enterococcus faecalis and Enterococcus faecium (Text)
has version: Antibacterial Activities of Rosmarinus officinalis Extract against Enterococcus faecalis and Enterococcus faecium (Text)
has published: Antibacterial Activities of Rosmarinus officinalis Extract against Enterococcus faecalis and Enterococcus faecium (Text)
subject: SF Animal culture

Antibacterial Activities of Rosmarinus officinalis Extract against Enterococcus faecalis and Enterococcus faecium (Text)
type: Document
has file: WVJ15(2)498-508,2025 (1).pdf
has part: WVJ15(2)498-508,2025 (1).pdf

Scienceline Publication
type: Organization

World’s Veterinary Journal
type: Collection
issn: 23224568

Eman Youssif Tohamy Elariny
type: Person
given name: Eman Youssif
family name: Tohamy Elariny

Eman Selem
type: Person
given name: Eman
family name: Selem

Nabawy Mostafa Elnabawy
type: Person
given name: Nabawy Mostafa
family name: Elnabawy

http://eprints.science-line.com/id/eprint/1569/
title: HTML Summary of #1569 <epc:when xmlns:epc="http://eprints.org/ep3/control" test="title">Antibacterial Activities of Rosmarinus officinalis Extract against Enterococcus faecalis and Enterococcus faecium</epc:when>
format: text/html
primary topic: Antibacterial Activities of Rosmarinus officinalis Extract against Enterococcus faecalis and Enterococcus faecium

SF Animal culture
type: Concept