eprintid: 1241
rev_number: 10
eprint_status: archive
userid: 5
dir: disk0/00/00/12/41
datestamp: 2025-02-07 20:09:00
lastmod: 2025-02-07 20:09:00
status_changed: 2025-02-07 20:09:00
type: article
metadata_visibility: show
creators_name: Florent Sèdégan, Enagnon Bienvenue
creators_name: Yao, Akpo
creators_name: Kadoéito, Cyrille Boko
creators_id: sedeganbienvenue@gmail.com
creators_id: sedeganbienvenue@gmail.com
creators_id: sedeganbienvenue@gmail.com
title: The Effects of Acute Oral Toxicity of Jatropha multifida and Hyptis suaveolens on Zootechnical Parameters in Local Chickens
ispublished: pub
subjects: SF
divisions: j13
full_text_status: public
keywords: Body weight, Lethal Dose, Local chicken, Medicinal plant, Mortality, Toxicity
abstract: The substantial use of medicinal plants in traditional poultry farming is a well-established practice. The present study aimed to determine the median lethal dose (LD50) of ethanolic extracts of Jatropha multifida and Hyptis suaveolens in local chickens and to assess the effects of these extracts on feed intake, water intake, and average body weight. The methodology followed OECD Directive 223, which involves administering the highest dose of the extract to the chickens and assessing any mortality. Three homogeneous groups of five chickens each were formed for the limit dose test. The control group received distilled water, while batches 1 and 2 received 700 mg of ethanolic extract of J. multifida and H. suaveolens, respectively. The average body weight of the chickens was 350g ± 20, and the extracts were administered via gavage at a suspension of 2000 mg/kg.bwt of the extract dissolved in water. The results of the phytochemical tests indicated the presence of several chemical compounds known for their therapeutic effects. The productivity of the extract was 2.75 ± 0.19 for J. multifida and 3.3 ± 0.27 for H. suaveolens. After administration of the suspensions, observation for 14 days revealed no mortality. This finding indicated that the LD50 of the utilized ethanolic extracts exceeds the limit dose (2000 mg/kg.bwt). However, feed intake (49 ± 3 > 46±4) and average body weight (436 ± 31 > 388 ± 37) in batch 2 were significantly higher than those in batch 1. Future research should explore the subacute toxicity of J. multifida and H. suaveolens across various chicken breeds.
date: 2024-09-25
publication: World's Veterinary Journal
volume: 14
number: 3
publisher: SCIENCELINE
pagerange: 328-337
refereed: TRUE
issn: 2322-4568
official_url: https://www.scopus.com/record/display.uri?eid=2-s2.0-85206315175&origin=resultslist&sort=plf-f&src=s&sid=d1cddfd490a93522df08bf7f6d0da4f3&sot=a&sdt=a&s=SOURCE-ID+%2821100842862%29AND%28%28+PUBYEAR+%3D+2024%29+OR+%28+PUBYEAR+%3D+2023%29+OR+%28+PUBYEAR+%3D+2022%29+OR+%28+PUBYEAR+%3D+2021%29%29AND+%28%28++DOCTYPE+%28+ar+%29++OR++DOCTYPE+%28+re+%29++OR++DOCTYPE+%28+cp+%29++OR++DOCTYPE+%28+dp+%29++OR++DOCTYPE+%28+ch+%29++%29+AND+NOT+DOCTYPE+%28+undefined+%29%29+AND++NOT+PUBSTAGE+%28+aip+%29++&sl=272&sessionSearchId=d1cddfd490a93522df08bf7f6d0da4f3&relpos=11
j_index: scopus
citation:    (2024)     The Effects of Acute Oral Toxicity of Jatropha multifida and Hyptis suaveolens on Zootechnical Parameters in Local Chickens.   World's Veterinary Journal.  pp. 328-337.  ISSN 2322-4568   
document_url: http://eprints.science-line.com/id/eprint/1241/1/WVJ%2014%283%29%20328-337%2C%202024%20%281%29.pdf
document_url: http://eprints.science-line.com/id/eprint/1241/2/WVJ%2014%283%29%20328-337%2C%202024.pdf