…
comment: The repository administrator has not yet configured an RDF license.
primary topic: The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens

The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens
type: AcademicArticle
type: Article
abstract: The production of traditional synthesized calcium D-pantothenate (D-PA) is accompanied with chemical pollution, therefore, the eco-friendly bio-fermentation technology has received widespread attention. In order to verify the safety of a novel D-PA product produced by genetically engineered bacteria (Escherichia coli K12), the authors of the current study investigated the influence of adding D-PA to the diet on growth performance and health status of broiler chickens. A total of 192 day-old healthy Arbor Acres broiler chickens with similar weight (43.21 ± 0.12 g) were randomly divided into 4 treatments with 6 replicates and 8 broiler chickens in each replicate (male and female in half). The Escherichia coli K12 was genetically engineered for the production of D-PA. The control group was fed with the basal diet containing 20 mg/kg synthesized D-PA (CT group). The treatments were supplemented with 20 (TCaP1 group, recommended dose group), 100 (TCaP5 group, 5-fold-dose group), and 200 (TCaP10 group, 10-fold-dose group) mg/kg bio-based D-PA product, respectively. The experiment lasted for 42 days and the growth performance and health status of broiler chickens were determined. The results indicated that the addition of 5- and 10-fold doses of bio-based D-PA could increase the average daily weight gain during 22–42 days of age and decrease the feed conversion rate during 22–42 and 1–42 days of age of broilers. There were some differences in white blood cell count, intermediate cell absolute value (MID) count, absolute granulocyte count, absolute lymphocyte count, granulocyte percentage, mean corpuscular volume, red blood cell distribution width-standard deviation, mean platelet volume and serum phosphorus and total bilirubin in different groups, compared with the CT group. Histological observations of the liver, spleen, pancreas, and small intestines showed that the tissue structures of various organs of the broiler chickens fed with the bio-based D-PA were clear, and no…
date: 2024-06-30
volume: 14
issue: 2
is part of: Journal of World's Poultry Research
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
has document: The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens (Text)
has version: The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens (Text)
has published: The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens (Text)
has document: The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens (Other)
subject: SF Animal culture

The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens (Text)
type: Document
has file: JWPR14(2) 160-171, 2024.pdf
has part: JWPR14(2) 160-171, 2024.pdf

Scienceline Publication
type: Organization

Journal of World's Poultry Research
type: Collection
issn: 2322455X

C. Li
type: Person
given name: C.
family name: Li

L. Zhang
type: Person
given name: L.
family name: Zhang

M. Li
type: Person
given name: M.
family name: Li

G. Liu
type: Person
given name: G.
family name: Liu

X. Xu
type: Person
given name: X.
family name: Xu

H. Zhang
type: Person
given name: H.
family name: Zhang

The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens (Other)
type: Document
is version of: The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens (Text)
is volatile version of: The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens (Text)
is index codes version of: The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens (Text)
has file: indexcodes.txt
has part: indexcodes.txt

http://eprints.science-line.com/id/eprint/1153/
title: HTML Summary of #1153 <epc:when xmlns:epc="http://eprints.org/ep3/control" test="title">The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens</epc:when>
format: text/html
primary topic: The Safety Evaluation of Novel Bio-based Calcium D-pantothenate Obtained from Recombinant Escherichia coli K12 on Growth Performance and Health Status of Broiler Chickens

SF Animal culture
type: Concept