TY  - JOUR
TI  - Association of Antiseptic Resistance Gene (qacE?1) with Class 1 Integrons in Salmonella Isolated from Broiler Chickens
SP  - 214
SN  - 2322455X (ISSN)
EP  - 222
KW  - intI1
KW  -  Multidrug-resistant Salmonella
KW  -  PCR
KW  -  qacE?1
AV  - public
A1  - Ali, N. M.
A1  - Mohamed, F. M.
IS  - 2s
PB  - Scienceline Publication, Ltd
JF  - Journal of World's Poultry Research
VL  - 10
Y1  - 2020/06/14/
ID  - eprints103
N2  - Salmonella enterica is considered a zoonotic pathogen that acquires antibiotic resistance in livestock. In the current study, a total of 18 Salmonella enterica isolates recovered from cloacal swabs of diseased and freshly dead broilers were serotyped and assessed for susceptibility to clinically important antibiotics. The multi-resistant isolates were examined for the presence of the antiseptic resistance genes including quaternary ammonium (qacE?1) and class 1 integron-integrase (intI1) by PCR. The results of serotyping of 18 Salmonella isolates indicated that five isolates belonged to Salmonella Typhimurium, four isolates belonged to each of Salmonella Kentucky and Salmonella Enteritidis, three isolates belonged to Salmonella Molade and one isolate belonged to each of Salmonella Inganda and Salmonella Larochelle. Fifteen Salmonella isolates (83.3%) were multi-resistant to at least three antibiotics with a multidrug resistance index value of 0.473. All of the intI1-positive strains carried qacE?1, confirming that the qacE?1 gene is linked to the integrons. The study concluded that the presence of the qacE?1 resistance gene and class 1 integrase in multi-drug resistant Salmonella strains might be contributed to co-resistance or cross-resistance mechanisms.
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099907968&doi=10.36380%2fJWPR.2020.27&partnerID=40&md5=61eccf7cc47beb1b6b86762be765e539
ER  -